Lees-Miller, Susan: search on Z-Library

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1

Uncovering DNA-PKcs ancient phylogeny, unique sequence motifs and insights for human disease

Lees-Miller, James P., Cobban, Alexander, Katsonis, Panagiotis, Bacolla, Albino, Tsutakawa, Susan E., Hammel, Michal, Meek, Katheryn, Anderson, Dave W., Lichtarge, Olivier, Tainer, John A., Lees-Mille

Journal:

Progress in Biophysics and Molecular Biology

Year:

2020

File:

PDF, 70.03 MB

2020

2

Dissection of DNA double-strand-break repair using novel single-molecule forceps

Wang, Jing L., Duboc, Camille, Wu, Qian, Ochi, Takashi, Liang, Shikang, Tsutakawa, Susan E., Lees-Miller, Susan P., Nadal, Marc, Tainer, John A., Blundell, Tom L., Strick, Terence R.

Journal:

Nature Structural and Molecular Biology

Year:

2018

Language:

english

File:

PDF, 1.96 MB

english, 2018

3

The C-terminus of Nej1 is critical for nuclear localization and non-homologous end-joining

Mahaney, Brandi L., Lees-Miller, Susan P., Cobb, Jennifer A.

Journal:

Year:

2014

Language:

english

File:

PDF, 2.10 MB

english, 2014

4

Identification of in vitro and in vivo phosphorylation sites in the catalytic subunit of the DNA-dependent protein kinase

DOUGLAS, Pauline, SAPKOTA, Gopal P., MORRICE, Nick, YU, Yaping, GOODARZI, Aaron A., MERKLE, Dennis, MEEK, Katheryn, ALESSI, Dario R., LEES-MILLER, Susan P.

Journal:

Biochemical Journal

Year:

2002

Language:

english

File:

PDF, 299 KB

english, 2002

5

Resistance of Actin to Cleavage during Apoptosis

Qizhong Song, Tie Wei, Susan Lees-Miller, Emad Alnemri, Dianne Watters and Martin F. Lavin

Journal:

Proceedings of the National Academy of Sciences

Year:

1997

Language:

english

File:

PDF, 1.36 MB

english, 1997

6

Noncoding RNA joins Ku and DNA-PKcs for DNA-break resistance in breast cancer

Lees-Miller, Susan P, Beattie, Tara L, Tainer, John A

Journal:

Nature Structural and Molecular Biology

Year:

2016

Language:

english

File:

PDF, 222 KB

english, 2016

7

Inactivation of DNA-Dependent Protein Kinase by Protein Kinase Cδ: Implications for Apoptosis

Bharti, Ajit, Kraeft, Stine-Kathrein, Gounder, Mrinal, Pandey, Pramod, Jin, Shengfang, Yuan, Zhi-Min, Lees-Miller, Susan P., Weichselbaum, Ralph, Weaver, David, Chen, Lan Bo, Kufe, Donald, Kharbanda,

Journal:

Molecular and Cellular Biology

Year:

1998

Language:

english

File:

PDF, 1.40 MB

english, 1998

8

DNA requirements for interaction of the C-terminal region of Ku80 with the DNA-dependent protein kinase catalytic subunit (DNA-PKcs)

Radhakrishnan, Sarvan Kumar, Lees-Miller, Susan P.

Journal:

Year:

2017

Language:

english

File:

PDF, 1.15 MB

english, 2017

9

DNA-dependent protein kinase promotes DNA end processing by MRN and CtIP

Deshpande, Rajashree A., Myler, Logan R., Soniat, Michael M., Makharashvili, Nodar, Lee, Linda, Lees-Miller, Susan P., Finkelstein, Ilya J., Paull, Tanya T.

Journal:

Science Advances

Year:

2020

File:

PDF, 3.12 MB

2020

10

ATM-Deficient Cancers Provide New Opportunities for Precision Oncology

Jette, Nicholas R., Kumar, Mehul, Radhamani, Suraj, Arthur, Greydon, Goutam, Siddhartha, Yip, Steven, Kolinsky, Michael, Williams, Gareth J., Bose, Pinaki, Lees-Miller, Susan P.

Journal:

Year:

2020

Language:

english

File:

PDF, 1.56 MB

english, 2020

11

Prognostic significance of p16 in locally advanced squamous cell carcinoma of the head and neck treated with concurrent cisplatin and radiotherapy

Harold Y. Lau, Sony Brar, Alexander C. Klimowicz, Stephanie K. Petrillo, Desirée Hao, Nigel T. Brockton, Christina S. Kong, Susan P. Lees-Miller, Anthony M. Magliocco

Journal:

Year:

2011

Language:

english

File:

PDF, 328 KB

english, 2011

12

DNA double strand breaks: Not all foci are created equal

Cobb, Jennifer A., Lees-Miller, Susan

Journal:

Year:

2010

Language:

english

File:

PDF, 640 KB

english, 2010

13

Choreographing the DNA Damage Response: PP6 joins the dance

Douglas, Pauline, Moorhead, Greg, Xu, Xingzhi, Lees-Miller, Susan

Journal:

Year:

2010

Language:

english

File:

PDF, 368 KB

english, 2010

14

Significance of Co-expression of Epidermal Growth Factor Receptor and Ki67 on Clinical Outcome in Patients With Anal Cancer Treated With Chemoradiotherapy: An Analysis of NRG Oncology RTOG 9811

Doll, Corinne M., Moughan, Jennifer, Klimowicz, Alexander, Ho, Clement K., Kornaga, Elizabeth N., Lees-Miller, Susan P., Ajani, Jaffer A., Crane, Christopher H., Kachnic, Lisa A., Okawara, Gordon S.,

Journal:

International Journal of Radiation Oncology*Biology*Physics

Year:

2017

Language:

english

File:

PDF, 1.56 MB

english, 2017

15

A structural model for regulation of NHEJ by DNA-PKcs autophosphorylation

Tracey A. Dobbs, John A. Tainer, Susan P. Lees-Miller

Journal:

Year:

2010

Language:

english

File:

PDF, 862 KB

english, 2010

16

XLF Regulates Filament Architecture of the XRCC4·Ligase IV Complex

Michal Hammel, Yaping Yu, Shujuan Fang, Susan P. Lees-Miller, John A. Tainer

Journal:

Year:

2010

Language:

english

File:

PDF, 2.13 MB

english, 2010

17

Analysis of DNA-Dependent Protein Kinase-Mediated DNA End Joining by Two-Photon Fluorescence Cross-Correlation Spectroscopy

Merkle, Dennis, Block, Wesley D., Yu, Yaping, Lees-Miller, Susan P., Cramb, David T.

Journal:

Year:

2006

Language:

english

File:

PDF, 249 KB

english, 2006

18

Relative affinities of poly(ADP-ribose) polymerase and DNA-dependent protein kinase for DNA strand interruptions

Icy D’Silva, Joëlle D Pelletier, Jean Lagueux, Damien D’Amours, M.Ahmad Chaudhry, Michael Weinfeld, Susan P Lees-Miller, Guy G Poirier

Journal:

Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology

Year:

1999

Language:

english

File:

PDF, 197 KB

english, 1999

19

PIK3CA mutational status and overall survival in patients with cervical cancer treated with radical chemoradiotherapy

McIntyre, John B., Wu, Jackson S., Craighead, Peter S., Phan, Tien, Köbel, Martin, Lees-Miller, Susan P., Ghatage, Prafull, Magliocco, Anthony M., Doll, Corinne M.

Journal:

Gynecologic Oncology

Year:

2013

Language:

english

File:

PDF, 525 KB

english, 2013

20

GC box binding induces phosphorylation of Sp1 by a DNA-dependent protein kinase

Stephen P. Jackson, Judy J. MacDonald, Susan Lees-Miller, Robert Tjian

Journal:

Year:

1990

Language:

english

File:

PDF, 1.97 MB

english, 1990

21

Protein-DNA Complexes Containing DNA-Dependent Protein Kinase in Crude Extracts from Human and Rodent Cells

Nicholas S. Y. Ting, Doug W. Chan, Lauri G. Lintott, Joan Allalunis-Turner and Susan P. Lees-Miller

Journal:

Radiation Research

Year:

1999

Language:

english

File:

PDF, 2.08 MB

english, 1999

22

Low ATM protein expression and depletion of p53 correlates with olaparib sensitivity in gastric cancer cell lines

Kubota, Eiji, Williamson, Christopher T, Ye, Ruiqiong, Elegbede, Anifat, Peterson, Lars, Lees-Miller, Susan P, Bebb, D Gwyn

Journal:

Year:

2014

Language:

english

File:

PDF, 2.32 MB

english, 2014

23

Dimerization and DNA Binding Alter Phosphorylation of Fos and Jun

Cory Abate, Suzanne J. Baker, Susan P. Lees-Miller, Carl W. Anderson, Daniel R. Marshak and Tom Curran

Journal:

Proceedings of the National Academy of Sciences

Year:

1993

Language:

english

File:

PDF, 1.13 MB

english, 1993

24

The non-homologous end-joining factor Nej1 inhibits resection mediated by Dna2-Sgs1 at DNA double strand breaks

Sorenson, Kyle S., Mahaney, Brandi L., Lees-Miller, Susan P., Cobb, Jennifer A.

Journal:

Journal of Biological Chemistry

Year:

2017

Language:

english

File:

PDF, 2.35 MB

english, 2017

25

Phosphorylation at Ser-15 and Ser-392 in Mutant p53 Molecules from Human Tumors is Altered Compared to Wild-Type p53

Stephen J. Ullrich, Kazuyasu Sakaguchi, Susan P. Lees-Miller, Michele Fiscella, W. Edward Mercer, Carl W. Anderson and Ettore Appella

Journal:

Proceedings of the National Academy of Sciences

Year:

1993

Language:

english

File:

PDF, 1.27 MB

english, 1993

26

Combined poly-ADP ribose polymerase and ataxia-telangiectasia mutated/Rad3-related inhibition targets ataxia-telangiectasia mutated-deficient lung cancer cells

Jette, Nicholas R., Radhamani, Suraj, Arthur, Greydon, Ye, Ruiqiong, Goutam, Siddhartha, Bolyos, Anthony, Petersen, Lars F., Bose, Pinaki, Bebb, D. Gwyn, Lees-Miller, Susan P.

Journal:

British Journal of Cancer

Year:

2019

Language:

english

File:

PDF, 1.23 MB

english, 2019

27

10.1038/29354

Lee, Patrick W. K., Woo, Richard A., McLure, Kevin G., Lees-Miller, Susan P., Rancourt, Derrick E.

Journal:

Year:

1998

Language:

english

File:

PDF, 91 KB

english, 1998

28

Putative homologues of the DNA-dependent protein kinase catalytic subunit (DNA-PKcs) and other components of the non-homologous end joining machinery in Dictyostelium discoideum

Wesley D. Block, Susan P. Lees-Miller

Journal:

Year:

2005

Language:

english

File:

PDF, 478 KB

english, 2005

29

DNA-Dependent Protein Kinase Phosphorylation Sites in Ku 70/80 Heterodimer †

Chan, Doug W., Ye, Ruiqiong, Veillette, Christian J., Lees-Miller, Susan P.

Journal:

Year:

1999

Language:

english

File:

PDF, 109 KB

english, 1999

30

Structure and Dynamics of Lipoplex Formation Examined Using Two-Photon Fluorescence Cross-Correlation Spectroscopy †

Merkle, Dennis, Lees-Miller, Susan P., Cramb, David T.

Journal:

Year:

2004

Language:

english

File:

PDF, 274 KB

english, 2004

31

The DNA-dependent protein kinase: A multifunctional protein kinase with roles in DNA double strand break repair and mitosis

Jette, Nicholas, Lees-Miller, Susan P.

Journal:

Progress in Biophysics and Molecular Biology

Year:

2015

Language:

english

File:

PDF, 1.70 MB

english, 2015

32

Phosphorylation of SAF-A/hnRNP-U Serine 59 by Polo-Like Kinase 1 Is Required for Mitosis

Douglas, Pauline, Ye, Ruiqiong, Morrice, Nicholas, Britton, Sébastien, Trinkle-Mulcahy, Laura, Lees-Miller, Susan P.

Journal:

Molecular and Cellular Biology

Year:

2015

Language:

english

File:

PDF, 7.12 MB

english, 2015

33

10.1038/3882

Khanna, Kum Kum, Keating, Katherine E., Kozlov, Sergei, Scott, Shaun, Gatei, Magtouf, Hobson, Karen, Taya, Yoichi, Gabrielli, Brian, Chan, Doug, Lees-Miller, Susan P., Lavin, Martin F.

Journal:

Nature Genetics

Year:

1998

Language:

english

File:

PDF, 157 KB

english, 1998

34

DNA-PK and ATM phosphorylation sites in XLF/Cernunnos are not required for repair of DNA double strand breaks

Yaping Yu, Brandi L. Mahaney, Ken-Ichi Yano, Ruiqiong Ye, Shujuan Fang, Pauline Douglas, David J. Chen, Susan P. Lees-Miller

Journal:

Year:

2008

Language:

english

File:

PDF, 1.05 MB

english, 2008

35

Erratum to “Dysfunction of lamin A triggers a DNA damage response and cellular senescence” [DNA Repair 5 (2006) 286–289]

Susan P. Lees-Miller

Journal:

Year:

2006

File:

PDF, 68 KB

2006

36

Biochemical characterization of the ataxia-telangiectasia mutated (ATM) protein from human cells

Aaron A Goodarzi, Susan P Lees-Miller

Journal:

Year:

2004

Language:

english

File:

PDF, 652 KB

english, 2004

37

Interaction of DNA-Dependent Protein Kinase and Poly(ADP-Ribose) Polymerase with Radiation-Induced DNA Strand Breaks

Michael Weinfeld, M. Ahmad Chaudhry, Damien D'Amours, Joëlle D. Pelletier, Guy G. Poirier, Lawrence F. Povirk and Susan P. Lees-Miller

Journal:

Radiation Research

Year:

1997

Language:

english

File:

PDF, 1.44 MB

english, 1997

38

Repair of ionizing radiation-induced DNA double-strand breaks by non-homologous end-joining

Mahaney, Brandi L., Meek, Katheryn, Lees-Miller, Susan P.

Journal:

Biochemical Journal

Year:

2009

Language:

english

File:

PDF, 538 KB

english, 2009

39

DNA end sequestration by DNA-dependent protein kinase and end joining of sterically constrained substrates in whole-cell extracts

Jae Wan Lee, Kedar V. Inamdar, Michele F. Hannah, Susan P. Lees-Miller, Lawrence F. Povirk

Journal:

Environmental and Molecular Mutagenesis

Year:

2003

Language:

english

File:

PDF, 278 KB

english, 2003

40

10.1038/29350

Lee, Patrick W. K., Woo, Richard A., McLure, Kevin G., Lees-Miller, Susan P., Rancourt, Derrick E.

Journal:

Year:

1998

Language:

english

File:

PDF, 268 KB

english, 1998

41

Mre11–Rad50–Nbs1 conformations and the control of sensing, signaling, and effector responses at DNA double-strand breaks

Gareth J. Williams, Susan P. Lees-Miller, John A. Tainer

Journal:

Year:

2010

Language:

english

File:

PDF, 1.06 MB

english, 2010

42

UV-light induces p38 MAPK-dependent phosphorylation of Bcl10

Amanda J Bodero, Ruiqiong Ye, Susan P Lees-Miller

Journal:

Biochemical and Biophysical Research Communications

Year:

2003

Language:

english

File:

PDF, 149 KB

english, 2003

43

The Significance of Tumoral ERCC1 Status in Patients With Locally Advanced Cervical Cancer Treated With Chemoradiation Therapy: A Multicenter Clinicopathologic Analysis

Doll, Corinne M., Aquino-Parsons, Christina, Pintilie, Melania, Klimowicz, Alexander C., Petrillo, Stephanie K., Milosevic, Michael, Craighead, Peter S., Clarke, Blaise, Lees-Miller, Susan P., Fyles,

Journal:

International Journal of Radiation Oncology*Biology*Physics

Year:

2013

Language:

english

File:

PDF, 742 KB

english, 2013

44

Structural insights into NHEJ: Building up an integrated picture of the dynamic DSB repair super complex, one component and interaction at a time

Williams, Gareth J., Hammel, Michal, Radhakrishnan, Sarvan Kumar, Ramsden, Dale, Lees-Miller, Susan P., Tainer, John A.

Journal:

Year:

2014

Language:

english

File:

PDF, 3.00 MB

english, 2014

45

ATM-Deficient Colorectal Cancer Cells Are Sensitive to the PARP Inhibitor Olaparib

Wang, Chen, Jette, Nicholas, Moussienko, Daniel, Bebb, D. Gwyn, Lees-Miller, Susan P.

Journal:

Translational Oncology

Year:

2017

Language:

english

File:

PDF, 678 KB

english, 2017

46

Comparing ERCC1 protein expression, mRNA levels, and genotype in squamous cell carcinomas of the head and neck treated with concurrent chemoradiation stratified by HPV status

Desirée Hao, Harold Y. Lau, Misha Eliasziw, Alan Box, Román Diaz, Alexander C. Klimowicz, Brian Shin, Susan P. Lees-Miller, Anthony M. Magliocco

Journal:

Year:

2012

Language:

english

File:

PDF, 1.31 MB

english, 2012

47

The double (strand break) life of Par-3

Lees-Miller, Susan P.

Journal:

Nature Cell Biology

Year:

2007

Language:

english

File:

PDF, 165 KB

english, 2007

48

Mo1930 ATM and P53 Expression Level Correlate With Sensitivity to Olaparib in Gastric Cancer

Kubota, Eiji, Williamson, Chris T., Lees-Miller, Susan P., Bebb, Gwyn

Journal:

Gastroenterology

Year:

2014

Language:

english

File:

PDF, 215 KB

english, 2014

49

DNA Double Strand Break Repair in Mitosis Is Suppressed by Phosphorylation of XRCC4

Lees-Miller, Susan P., Jinks-Robertson, Sue

Journal:

Year:

2014

Language:

english

File:

PDF, 254 KB

english, 2014

50

Fumarate in DNA repair

Lees-Miller, Susan P.

Journal:

Nature Cell Biology

Year:

2015

Language:

english

File:

PDF, 133 KB

english, 2015

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